A.C.E.’S- ADVANCED GLYCATION END PRODUCTS- WHAT ARE THEY, AND ARE THEY BAD FOR MY DOG?
Advanced Glycation End-products (AGEs) are compounds that are formed when protein or fat molecules react with sugar molecules through a process called glycation. High heat cooking, such as grilling, frying, or roasting, can increase the formation of AGEs in food. Some studies suggest that a high intake of AGEs may be associated with various health issues in humans, including inflammation, oxidative stress, and insulin resistance. However, the research on AGEs and their effects on dogs is limited.
While we don't have definitive evidence on the effects of AGEs on dogs, it's generally a good idea to avoid feeding dogs highly processed or overly cooked foods, as these foods may contain higher levels of AGEs. Feeding dogs a balanced, fresh food diet that includes whole foods, lean meats, and fresh vegetables and fruits can help reduce their exposure to AGEs and provide them with essential nutrients they need. Avoiding processed foods such as kibble, which is cooked at incredibly high heat levels is also best for your dog’s overall health.
Additionally, it's important to*note that cooking food is necessary to kill harmful bacteria and make some nutrients more bioavailable to dogs. The key is to balance the benefits of cooking with the potential risks of overcooking or highly processed foods. If you're concerned about the levels of AGEs in your dog's food, consider speaking with a licensed holistic or integrative veterinarian or canine nutritionist for guidance on appropriate feeding practices.
Some studies suggest that a high intake of AGEs may be associated with various health issues in humans, including inflammation, oxidative stress, and insulin resistance.
For example, a study published in the Journal of Clinical Endocrinology & Metabolism found that: people who consumed a high-AGE diet had higher levels of oxidative stress and inflammation, which are risk factors for chronic diseases such as cardiovascular disease and diabetes. Another study published in the American Journal of Clinical Nutrition found that a high intake of AGEs was associated with an increased risk of developing type 2 diabetes.
Research has also linked high levels of AGEs to other health issues such as kidney disease, Alzheimer's disease, and certain cancers. However, more research is needed to fully understand the effects of AGEs on human health as well as on canine health.
It's worth noting that not all AGEs are created equal, and the effects of different types of AGEs may vary. Some AGEs may have more harmful effects on health than others, depending on factors such as their chemical structure and how they are metabolized by the body.
Overall, while the evidence on the effects of AGEs on human health is still evolving, it's generally recommended to limit the intake of highly processed foods and foods cooked at high temperatures in order to reduce exposure to AGEs and other potentially harmful compounds.
The same hold true for other species of animals you have living with you as your family members.
*Note- as of this writing; April 2023, there is no law or regulation in the USA ‘requiring’ A.C.E.s to even be mentioned on any type of food labeling, albeit for humans or animals. This does not mean they are not present in our food. As we mentioned earlier in this article, to avoid them it is best to enjoy a WHOLE FOOD diet for both you and your pets.
